Projects

Clinic trails

Desensitization of Immunomodulating Agent-Related Hypersensitivity Reactions as a Means to Provide Therapeutic Options in the Management of Plasma Cell Disorders (DeHyperPCD)

PI:  Dr. Anca Prica, MD, Division of Medical Oncology and Hematology

Co-PI: Jack T. Seki R.Ph. BSc. (Pharm), PharmD Pharmacotherapy Specialist, Oncology

Statistician: Eshetu G. Atenafu, Biostatistics Department

Princess Margaret Cancer Centre, University Health Network

Sodium Bicarbonate Injections for Restoration of Flow in a Central Venous Catheter (CVC/Hickman Catheter) or Peripherally Inserted Central Venous Catheter (PICC)

PI:  Mark Minden MD, PhD. FRCPC, Division of Medical Oncology and Hematology

Co-PI: Jack T. Seki R.Ph. BSc. (Pharm), PharmD Pharmacotherapy Specialist, Oncology

Statistician: Eshetu G. Atenafu, Biostatistics Department

Princess Margaret Cancer Centre, University Health Network

Double-Blind, Placebo-Controlled Trial of Metformin in Reducing Progression Among Men on Expectant Management for Low Risk Prostate Cancer: The MAST (Metformin Active Surveillance Trial) Study

PI:  Neil Fleshner, MD, MPH, FRCSC

Statistician: Eshetu G. Atenafu, Biostatistics Department

NCI Experimental Therapeutics-Clinical Trials Network with Phase I Emphasis (ETCTN) (UM1) North American Star Consortium (NASC) 

PI: L Siu, Bedard; Biostatistics Lead: W Xu

Observational Studies

2020: Exploratory analysis of the prevalence of sleep apnea in the long-haul trucking population and its relationship to motor vehicle accidents

Continuous Alloreactive T cell depletion and Regulatory T cell Expansion for the treatment of steroid- refractory or dependent chronic GVHD - A multicenter phase II clinical trial – CNTRP-1401 (THE CARE TRIAL)

PI:  Imran Ahmad (Université de Montréal)

Co-PI: Dennis Kim (University, 

Statistician: Eshetu G. Atenafu, Biostatistics Department

2020: Exploratory analysis of eNose Breathomics data

2020: Evaluation of correlation between radiomics features and clinical outcomes

The 2BLAST Pipeline Development: (Biostatistical and Bioinformatic Longitudinal Analysis of Symptoms and Toxicities in cancer patients). PI: W Xu, G Liu

 

Artificial Intelligence, Data Science, and Microbiome Research. PI: PI: L Siu, B Haibe-Kains,W Xu, B Coburn

Methodology Development and Implementation for Microbiome Sequencing Data: Hierarchical Modeling on Clustered Taxa Counts with Repeated Measures. PI: W Xu

Translational & Biomarker Studies

UHN Princess Margaret Hospital