2021 Publications

MA Brett, EG Atenafu, N Singh, P Ghatage, BA Clarke, GS Nelson, .... Equivalent survival of p53 mutated endometrial endometrioid carcinoma grade 3 and endometrial serous carcinoma. International Journal of Gynecological Pathology. 40 (2), 116-123. 2021.

R Puckrin, EG Atenafu, JO Claudio, S Chan, V Gupta, D Maze, .... Measurable residual disease monitoring provides insufficient lead-time to prevent morphological relapse in the majority of patients with core-binding factor acute myeloid leukemia. haematologica. 106 (1). 2021.

 

S Lheureux, MC Cristea, JP Bruce, S Garg, M Cabanero, .... Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial. The Lancet. 397 (10271), 281-292. 2021.

 

T Spence, S Perera, J Weiss, S Grenier, L Ranich, F Shepherd, .... Clinical implementation of circulating tumour DNA testing for EGFR T790M for detection of treatment resistance in non-small cell lung cancer. Journal of Clinical Pathology. 74 (2), 91-97. 2021.

 

J Stewart, A Sahgal, Y Lee, H Soliman, CL Tseng, J Detsky, Z Husain, .... Quantitating interfraction target dynamics during concurrent chemoradiation for glioblastoma: a prospective serial imaging study. International Journal of Radiation Oncology* Biology* Physics. 109 (3), 736-746. 2021.

 

LA Chiarello, RJ Palisano, L Avery, S Hanna, On Track Study Team. Longitudinal trajectories and reference percentiles for participation in family and recreational activities of children with cerebral palsy. Physical & occupational therapy in pediatrics. 41 (1), 18-37. 2021.

 

C Liy-Wong, M Kim, AY Kirkorian, LF Eichenfield, LZ Diaz, A Horev, .... Hidradenitis suppurativa in the pediatric population: an international, multicenter, retrospective, cross-sectional study of 481 pediatric patients. JAMA dermatology. 157 (4), 385-391. 2021.

 

R Alblooshi, S Kanfar, B Lord, EG Atenafu, FV Michelis, I Pasic, A Gerbitz, .... Clinical prevalence and outcome of cardiovascular events in the first 100 days postallogeneic hematopoietic stem cell transplant. European Journal of Haematology. 106 (1), 32-39. 2021.

 

M Jiang, AF Fares, D Shepshelovich, P Yang, D Christiani, J Zhang, .... The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung …. Lung Cancer. 152, 58-65. 2021.

 

DS Tsang, L Kim, ZA Liu, L Janzen, M Khandwala, E Bouffet, N Laperriere, .... Intellectual changes after radiation for children with brain tumors: which brain structures are most important?. Neuro-oncology. 23 (3), 487-497. 2021.

 

P Munoz-Schuffenegger, A Barry, EG Atenafu, J Kim, J Brierley, J Ringash, .... Stereotactic body radiation therapy for hepatocellular carcinoma with Macrovascular invasion. Radiotherapy and Oncology. 156, 120-126. 2021.

 

SCM Lau, AF Fares, LW Le, KM Mackay, S Soberano, SW Chan, E Smith, .... Subtypes of EGFR-and HER2-Mutant Metastatic NSCLC Influence Response to Immune Checkpoint Inhibitors. Clinical Lung Cancer. . 2021.

 

RW Chan, H Chen, S Myrehaug, EG Atenafu, GJ Stanisz, J Stewart, .... Quantitative CEST and MT at 1.5 T for monitoring treatment response in glioblastoma: early and late tumor progression during chemoradiation. Journal of Neuro-Oncology. 151 (2), 267-278. 2021.

 

HM Cherniawsky, V Kukreti, D Reece, E Masih-Khan, A McCurdy, .... The survival impact of maintenance lenalidomide: an analysis of real-world data from the Canadian Myeloma Research Group national database. haematologica. 106 (6), 1733. 2021.

 

CJ Iasella, A Hoji, I Popescu, J Wei, ME Snyder, Y Zhang, W Xu, .... Type-1 immunity and endogenous immune regulators predominate in the airway transcriptome during chronic lung allograft dysfunction. American Journal of Transplantation. 21 (6), 2145-2160. 2021.

 

KL Zeng, A Sahgal, CL Tseng, S Myrehaug, H Soliman, J Detsky, .... Prognostic factors associated with surviving less than 3 months vs greater than 3 years specific to spine stereotactic body radiotherapy and late adverse events. Neurosurgery. 88 (5), 971-979. 2021.

 

MQ Salas, EG Atenafu, O Bascom, L Wilson, W Lam, AD Law, I Pasic, .... Pilot prospective study of Frailty and Functionality in routine clinical assessment in allogeneic hematopoietic cell transplantation. Bone Marrow Transplantation. 56 (1), 60-69. 2021.

 

W Kong, Y Zheng, W Xu, H Gu, J Wu. Biomarkers of Alzheimer’s disease in severe obstructive sleep apnea–hypopnea syndrome in the Chinese population. European Archives of Oto-Rhino-Laryngology. 278 (3), 865-872. 2021.

 

M Branion-Calles, K Teschke, M Koehoorn, O Espin-Garcia, MA Harris. Estimating walking and bicycling in Canada and their road collision fatality risks: The need for a national household travel survey. Preventive medicine reports. 22, 101366. 2021.

 

T Sananmuang, E Yu, J Su, B O'Sullivan, S Rathod, B Chan, E Bartlett, .... Pre-and Post-Radiotherapy Radiologic Nodal Features and Oropharyngeal Cancer Outcomes. The Laryngoscope. 131 (4), E1162-E1171. 2021.

 

N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, .... Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics. 53 (6), 817-829. 2021.

 

A Pilar, E Yu, J Su, B O'Sullivan, E Bartlett, JN Waldron, J Ringash, .... Prognostic value of clinical and radiologic extranodal extension and their role in the 8th edition TNM cN classification for HPV-negative oropharyngeal carcinoma. Oral Oncology. 114, 105167. 2021.

 

A Hosni, K Chiu, SH Huang, W Xu, J Huang, A Bayley, SV Bratman, J Cho, .... Non-operative management for oral cavity carcinoma: Definitive radiation therapy as a potential alternative treatment approach. Radiotherapy and Oncology. 154, 70-75. 2021.

 

A Berlin, M Lovas, T Truong, S Melwani, J Liu, ZA Liu, A Badzynski, .... Implementation and outcomes of virtual care across a tertiary cancer center during COVID-19. JAMA oncology. 7 (4), 597-602. 2021.

 

HJ Zhang, A Amid, LA Janzen, CI Segbefia, S Chen, U Athale, .... Outcomes of haemoglobin Bart’s hydrops fetalis following intrauterine transfusion in Ontario, Canada. Archives of Disease in Childhood-Fetal and Neonatal Edition. 106 (1), 51-56. 2021.

 

KS Jhaveri, S Sagheb, L Guimaraes, S Krishna, AF Ahari, O Espin-Garcia. Evaluation of Crohn disease activity using a potential abbreviated MRE protocol consisting of balanced steady-state free precession MRI only versus full-protocol MRE. American Journal of Roentgenology. 216 (2), 384-392. 2021.

 

AS Alotaibi, S Prem, S Chen, JH Lipton, DD Kim, A Viswabandya, .... Fresh vs. frozen allogeneic peripheral blood stem cell grafts: A successful timely option. American Journal of Hematology. 96 (2), 179-187. 2021.

 

S Ghai, A Finelli, K Corr, R Chan, S Jokhu, X Li, S McCluskey, .... MRI-guided focused ultrasound ablation for localized intermediate-risk prostate cancer: early results of a phase II trial. Radiology. 298 (3), 695-703. 2021.

 

D Hausner, C Tricou, J Mathews, D Wadhwa, A Pope, N Swami, .... Timing of palliative care referral before and after evidence from trials supporting early palliative care. The oncologist. 26 (4), 332-340. 2021.

 

PJ Maralani, S Myrehaug, H Mehrabian, AKM Chan, M Wintermark, .... Intravoxel incoherent motion (IVIM) modeling of diffusion MRI during chemoradiation predicts therapeutic response in IDH wildtype glioblastoma. Radiotherapy and Oncology. 156, 258-265. 2021.

 

KL Zeng, A Sahgal, ZA Husain, S Myrehaug, CL Tseng, J Detsky, .... Local control and patterns of failure for “Radioresistant” spinal metastases following stereotactic body radiotherapy compared to a “Radiosensitive” reference. Journal of Neuro-Oncology. 152 (1), 173-182. 2021.

 

DDH Kim, I Novitzky-Basso, TS Kim, EG Atenafu, D Forrest, L Savoie, .... Optimal duration of imatinib treatment/deep molecular response for treatment-free remission after imatinib discontinuation from a Canadian tyrosine kinase inhibitor …. British Journal of Haematology. 193 (4), 779-791. 2021.

 

DM Jiang, HW Sim, O Espin-Garcia, BA Chan, A Natori, CH Lim, .... Chemoradiotherapy Using Carboplatin plus Paclitaxel versus Cisplatin plus Fluorouracil for Esophageal or Gastroesophageal Junction Cancer. Oncology. 99 (1), 49-56. 2021.

 

M Lyu, Y Cheng, J Zhou, W Chong, Y Wang, W Xu, B Ying. Systematic evaluation, verification and comparison of tuberculosis-related non-coding RNA diagnostic panels. Journal of cellular and molecular medicine. 25 (1), 184-202. 2021.

 

RM Glicksman, U Metser, D Vines, J Valliant, Z Liu, PW Chung, .... Curative-intent Metastasis-directed Therapies for Molecularly-defined Oligorecurrent Prostate Cancer: A Prospective Phase II Trial Testing the Oligometastasis Hypothesis. European urology. . 2021.

 

H Hu, L Tan, YL Bi, W Xu, L Tan, XN Shen, XH Hou, YH Ma, Q Dong, .... Association between methylation of BIN1 promoter in peripheral blood and preclinical Alzheimer’s disease. Translational psychiatry. 11 (1), 1-13. 2021.

 

M Oliva, PHH Schneeberger, V Rey, M Cho, R Taylor, AR Hansen, .... Transitions in oral and gut microbiome of HPV+ oropharyngeal squamous cell carcinoma following definitive chemoradiotherapy (ROMA LA-OPSCC study). British journal of cancer. 124 (9), 1543-1551. 2021.

 

JL Bender, K Hueniken, L Eng, MC Brown, S Kassirian, I Geist, .... Internet and social media use in cancer patients: association with distress and perceived benefits and limitations. Supportive Care in Cancer. 1-9. 2021.

 

R Jain, W Xu. HDSI: High dimensional selection with interactions algorithm on feature selection and testing. PloS one. 16 (2), e0246159. 2021.

 

JR de Almeida, VS Kim, B O'Sullivan, DP Goldstein, SV Bratman, .... Comparing unilateral vs. bilateral neck management in lateralized oropharyngeal cancer between surgical and radiation oncologists: An international practice pattern survey. Oral Oncology. 114, 105165. 2021.

 

MJ Lee, VH Jayalath, W Xu, L Lu, SJ Freedland, NE Fleshner, .... Association between metformin medication, genetic variation and prostate cancer risk. Prostate cancer and prostatic diseases. 24 (1), 96-105. 2021.

 

GJ Nason, MAS Jewett, PJ Bostrom, H Goldberg, AR Hansen, PL Bedard, .... Long-term Surveillance of Patients with Complete Response Following Chemotherapy for Metastatic Nonseminomatous Germ Cell Tumor. European Urology Oncology. 4 (2), 289-296. 2021.

 

MQ Salas, EG Atenafu, AD Law, W Lam, I Pasic, C Chen, FV Michelis, .... Experience using anti-thymocyte globulin with post-transplantation cyclophosphamide for graft-versus-host disease prophylaxis in peripheral blood haploidentical stem cell …. Transplantation and Cellular Therapy. 27 (5), 428. e1-428. e9. 2021.

 

MAJ Iafolla, C Yang, V Chandran, M Pintilie, Q Li, PL Bedard, A Hansen, .... Predicting toxicity and response to pembrolizumab through germline genomic HLA class 1 analysis. JNCI cancer spectrum. 5 (1), pkaa115. 2021.

 

D Forner, K Hueniken, T Yoannidis, I Witterick, E Monteiro, G Zadeh, .... Psychometric testing of the Skull Base Inventory health-related quality of life questionnaire in a multi-institutional study of patients undergoing open and endoscopic surgery. Quality of Life Research. 30 (1), 293-301. 2021.

 

K Mastrocostas, S Fischer, P Munoz-Schuffenegger, HJ Jang, LA Dawson, .... Radiological tumor response and histopathological correlation of hepatocellular carcinoma treated with stereotactic body radiation therapy as a bridge to liver transplantation. Abdominal Radiology. 46 (4), 1572-1585. 2021.

 

ZW Veitch, D Shepshelovich, C Gallagher, L Wang, AR Abdul Razak, .... Underreporting of symptomatic adverse events in phase I clinical trials. JNCI: Journal of the National Cancer Institute. . 2021.

 

W Xu, SH Huang, J Su, S Gudi, B O'Sullivan. Statistical fundamentals on cancer research for clinicians: Working with your statisticians. Clinical and Translational Radiation Oncology. . 2021.

 

O Espin-Garcia, RV Craiu, SB Bull. Two-phase sample selection strategies for design and analysis in post-genome wide association fine-mapping studies. medRxiv. . 2021.

 

L Avery, A Macpherson, S Flicker, M Rotondi. A review of reported network degree and recruitment characteristics in respondent driven sampling implications for applied researchers and methodologists. Plos one. 16 (4), e0249074. 2021.

Noel, C.W., Keshavarzi, S., Forner, D., Stephens, R., Watson, E., Monteiro, E., Hosni, A., Hansen, A., Goldstein, D.P. & de Almeida, J.R. 2021 Construct Validity of the EuroQoL-5 and the Health Utilities Index in Patients with Head and Neck Cancer. Otolaryngology – Head and Neck Surgery.  Accepted 2021 June 17. In press. Impact factor:1.85. Coauthor

 

Daniel V Araujo, Thiago Pimentel Muniz, Anjie Yang, Sareh Keshavarzi, Hadas Sorotsky, Marcus O Butler, Samuel Saibil, Anna Spreafico, David Hogg, Real World Outcomes and Hepatotoxicity of Infliximab in the Treatment of Steroid-Refractory Immune-Related Adverse Events. Current Oncology 2021, 28(3): 2173-2179. Impact factor:2.26. Coauthor

 

Jeanna M McCuaig, Emily Thain, Janet Malcolmson, Sareh Keshavarzi, Susan Randall Armel, Raymond H Kim Counseling matters: A comparison of patient reported outcomes following consent and result disclosure using an oncologist or genetic counselor mediated genetic testing model, Current Oncology, 2021 April 6, Impact factor:2.26. Coauthor

 

Sareh Keshavarzi, Barbara H. Braffett, Rose Gubitosi-Klug, Elsayed Soliman, Annette Barnie, Gayle Lorenzi, Rodica Pop-Busui, Amy Saenger, Trevor Orchard, Samuel Dagogo-Jack, Andrew Paterson. Risk Factors for Longitudinal Resting Heart Rate and its Associations with Cardiovascular Outcomes in the Diabetes Control and Complications / Epidemiology of Diabetes Interventions and Complications Study. Diabetes Care. 2021 Feb 25, https://doi.org/10.2337/dc20-2387. “In Press”. Impact Factor 16.02. Principal Author.

 

Bebu I, Keshavarzi S, Gao X, Braffett BH, Canty A, Herman W, Orchard T, Dagogo-Jack S, Lachin JM, Nathan D, Paterson A. Genetic Risk Factors for Cardiovascular Diseases in Type 1 Diabetes: the DCCT/EDIC Study. Diabetes Care. 2021 March 6. “In Press”. Impact Factor 16.02. Co-principal Author

 

Ahmed M. Elamir, Shawn Hutchinson, Hamzeh Albaba, Sareh Keshavarzi, Wei Xu, Carol-Anne Moulton, Ian McGilvary, Jennifer Knox, Grainne O'Kane, Rebecca M. Prince, Sangeetha Kalimuthu, John Kim, Jolie Ringash, Laura A. Dawson, Rebecca Wong, Aisling. A risk score model for locoregional recurrence following upfront surgery for pancreatic adenocarcinoma: implications for adjuvant therapy. Clinical Oncology, 2021 March 2, “In Press”. Impact Factor 3.5.  Coauthor

 

Justin M. Burgener, Jinfeng Zou, Zhen Zhao, Yangqiao Zheng, Roxana Y. Shen, Shao Hui Huang, Sareh Keshavarzi, Aaron M. Newman, Ash A. Alizadeh, Maximilian Diehn, Michael Hoffman, Wei Xu, Fei-Fei Liu, Geoffrey Liu, John N. Waldron, Ilan Weinreb, Anna Spreafico, Lillian L. Siu, John de Almeida, David Goldstein, Daniel D. De Carvalho, and Scott. V. Bratman. Tumor-naïve multimodal profiling of circulating tumor DNA in localized head and neck squamous cell carcinoma, Clinical Cancer Research, 2021 February 28, “In Press”, impact factor:10.1. Coauthor

T Pittman. Care deficiencies and super-organization of American nursing homes in hospital referral region. Frontiers in Public Health. 8, 1047-1059. 2021.